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99.99£¥ High Purity Natural hemp extract Cannabidiol CBD isolate Powder/13956-29-1
Time:2019/11/8 9:37:22 Hit:808
Cannabidiol ((-)-Cannabidiol), CBD for short, with the molecular formula C21H30O2, is a white crystalline powder extracted from industrial hemp, soluble in organic solvents such as ethanol, methanol, ether, benzene, chloroform, etc.
Chinese name: Cannabidiol
English name: (-)-Cannabidiol
English alias: CANNABIDIOL;
CAS Number: 13956-29-1
Molecular formula: C21H30O2
Molecular weight: 314.46200
Accurate quality: 314.22500
PSA: 40.46000
LogP: 5.84650
Refractive index: 1.545
Flash point: 206.3oC
Boiling point: 463.9oCat760mmHg
Density: 1.025g/cm3
Vapor pressure: 3.14E-09mmHgat25¡ãC
Storage conditions: 2-8¡æ
Content: 99%
Appearance: white crystalline powder or pale yellow resin or paste, melting point 66-67¡ã, [¦Á]27/D-125¡ã (0.066 g dissolved in 5 ml of 95% ethanol), almost insoluble in water or 10% Sodium hydroxide solution. Soluble in ethanol, methanol, ether, benzene, chloroform and petroleum ether.
1. The biosynthetic pathway of cannabidiol: the synthesis of the C10 terpene part in the CBD chemical structure is mainly through the phosphate deoxyxylulose pathway, and the phenol part comes from the polyketide-type reaction sequence (polyketide-type reaction sequence), and is believed to be fragrant. Leaf based diphosphate (GPP) and polyacetate olivetolic acid (OA) are special intermediates in the synthesis of cannabis chemical components. People have discovered CBD synthase that synthesizes CBD from cannabidiol (CBG). Firstly, isopentenyl diphosphate (IPP) and dimethyl propenyl diphosphate (DMAPP) react, and the generated GPP reacts with OA to generate CBG. CBG generates CBD, THC and its carboxylic acid compounds under the action of CBD synthase.
2. The chemical synthesis pathway of cannabidiol: There are many reports on the chemical synthesis pathway of cannabidiol, the most classic synthesis method (Figure 3): p-mentha-2,8-dien-1-ol is catalyzed by BF3 and In the olivetol reaction, three products were obtained, and the yield of (-)-CBD was 41%. Because the raw materials are relatively easy to obtain, the reaction is simple, and the yield of (-)-CBD is also high, it has been used as a common method for the synthesis of (-)-CBD for a long period of time.
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